Polybrominated diphenyl ethers and arylhydrocarbon... [Toxicol Lett. 2010] - PubMed result

I have previously expressed how the AhR (aryl hydrocarbon) may be an important factor in multiple chemical sensitivity....Since little is actually known about this important receptor -- it would be beneficial to understand more about how it regulates the Nrf2 and other immune reaction....

PBDEs did not activate but rather inhibited AhR signaling and specifically induced malformations in zebrafish embryos, which differ from those provoked by AhR agonists. Furthermore, BDE47 and TBDF differentially regulated global gene expression in hepatoma cells. Hence, PBDEs and AhR agonists trigger different toxicity and target gene expression."

Link: Polybrominated diphenyl ethers and arylhydrocarbon... [Toxicol Lett. 2010] - PubMed result: ").